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DETC - 5g

84.00 EUR
Model: NOX-10.2-5g
Manufactured by: Noxygen

Synonym:	Diethyldithiocarbamic acid sodium salt
Appearance:	White Solid
Chemical Structure:	C₅H₁₀NNaS₂· 3H₂
MW:	225.31
Purity:	99%
Solubility:	Water
Storage:	-20°C

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Biochem/physiol Actions	Inhibits induction of macrophage nitric oxide synthase.
Application	Spin trap used in conjunction with Fe²⁺to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO₂has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.
Miscellaneous	Reagent used for the extraction of trace metals into organic solvents for atomic absorption spectroscopy; Precipitation of trace metals for X-ray fluorescence spectroscopy

K.L. Cheng et al.,Handbook of Organic Analytical Reagents Boca Raton, p. 389 (1982)
W. Klemm et al.,Fres. Z. Anal. Chem. 364, 429 (1999)
S. Brüggerhoff et al.,Fres. Z. Anal. Chem. 311, 252 (1982)
Minakata, K., Quantification of copper in biological materials by use of electron spin resonance. Clin. Chem. 47, 1863 (2001)
Vanin, A.F., Iron diethyldithiocarbamate as spin trap for nitric oxide detection. Meth. Enzymol. 301, 269 (1999)
Wallis, G.,In vivospin trapping of nitric oxide generated in the small intestine, liver, and kidney during the development of endotoxemia: a time-course study. Shock 6, 274 (1996)
James, P.E., Simultaneous measurement of NO(*) and PO₂from tissue byin vivoEPR. Nitric Oxide 3, 292 (1999)